PeptideWorks Tryptic Protein Digestion Kits

PeptideWorks Tryptic Protein Digestion Kits
                                                    

Rapid, automatable, and robust protein digestion workflow
Peptide mapping for biotherapeutic proteins relies on protein digestion which includes the enzymatic treatment of a protein to produce peptide fragments to further characterize specific peptide regions and modifications. The results of protein digests are essential for protein structural characterization, protein identification, and protein modification monitoring including post-translation modifications, product related impurities, and multi-attribute monitoring (MAM) methods. However, sample preparation for peptide mapping is complex, laborious often with long digestion times.

Waters PeptideWorks Tryptic Protein Digestion Kits for manual or automated workflows uniquely provide your lab with high efficiency, reproducible peptide maps in under 2.5 hours4x faster than average home-brew methods. Achieve a 78% reduction in missed cleavages and a 98% reduction in contaminated autolysis peaks, which can further complicate data processing. When you combine PeptideWorks with Waters MaxPeak Premier Peptide Columns, you maximize sensitivity while minimizing problematic metal adsorption of acidic deamidated peptides in LC-UV and LC-MS chromatography.